What is the EXERT Study?

The EXERT study is a national, 18-month long, clinical trial to test whether physical exercise can slow the progression of mild memory loss and/or mild cognitive impairment in older adults between the ages of 65-89. It is a Phase III randomized, controlled trial examining the effects of exercise on cognitive function and on biological markers in older adults with mild memory loss. The EXERT study will test whether aerobic training, or stretching/balance/range of motion exercise, can improve memory and thinking skills and other measures of brain health in people with mild memory loss or lapses.

The EXERT Study is enrolling adults between the ages of 65 and 89 years who:

  • Are experiencing mild memory loss or lapses and/or are diagnosed with Mild Cognitive Impairment
  • Have not been exercising regularly
  • Are in good health otherwise to participate in the study.

What would be expected of me if I enroll in the EXERT study?

After completing a variety of tests during the screening phase, eligible adults will enroll in the EXERT study and be randomly assigned to either a stretching/balance/range of motion group or to an aerobic training group.

Those enrolled will exercise at participating local YMCAs, under the supervision of a personal trainer. Participants will complete their assigned exercise program four times per week for 18 months. In the first 12 months of the study, two of the four weekly sessions will be supervised by the trainer. In the final six months, participants will continue to complete their assigned exercise program at the YMCA, but without supervision.

What’s great about the EXERT study?

  • An 18-month membership to a participating YMCA
  • A personal trainer for 12 months
  • A personalized exercise program
  • A chance to feel better and have fun!

How do I enroll? 

There are many academic medical centers and specialty clinics across North America participating in the EXERT Study. Please refer to your nearest site location in order to learn more about enrolling in the study. 

In the News

Check out news articles of interest related to the EXERT Study, exercise and Alzheimer’s Disease.

EXERT Near You

The EXERT study has multiple sites locations across North America, each set up to evaluate potential participants for the EXERT study.

Ready to enroll?

Are you or someone you know the right fit for the EXERT Study? See if there is a site near you and/or find other opportunities to participate in clinical research related to memory loss and Alzheimer’s disease.